13th May 2022

How is THC-O Made?

Remember back in the day when the hemp industry only really consisted of CBD? Fast forward to 2022 and we find ourselves in a $4.7 billion dollar industry where brands and products are springing up left and right. From this recent explosion of products also comes a newer hemp-derived cannabinoid to enter the mainstream: THC-O.

THC-O, or THC-O Acetate is a naturally occurring, minor cannabinoid that exists within the hemp plant. Despite the cannabinoid being naturally-derived, brands convert CBD into Delta-8 and add other compounds into the mix to effectively synthesize THC-O. Upon consumption, its effects are three to four times more potent than traditional Delta-9 THC and resembles more of a low-potency LSD trip more so than a stoned feeling.

Despite THC-O’s entrance into the market, not much is known about the cannabinoid. Sure, it is a hemp-derived cannabinoid thus making it federally legal, and anecdotal evidence paints a telling story of what someone would experience upon consuming it. But with little to no regulation or bona fide research behind it, people may be skeptical. So this is what we’ll focus on today.

Today, we’d like to focus on how THC-O is made from the perspective of a hemp manufacturer such as Eighty Six Group that develops and distributes psychoactive hemp products for all to enjoy! At the end of the day, we’d want you to go into trying these products with as much information as possible so you know exactly what you’re getting yourself into. Let’s dive in!

THC-O, or THC-O Acetate is a naturally occurring minor cannabinoid found in the hemp plant. As a minor cannabinoid, however, producing commercial quantities of it to be used as part of the THC-O Disposables Series requires a little more finesse.

Similar to Delta-8 THC, which is also a minor cannabinoid where producing enough volume is an issue, THC-O is synthesized by converting CBD, the most abundant cannabinoid in hemp, into Delta-8 which is then further refined into THC-O. Here’s how the typical process would work:

  1. Industrial hemp is cultivated from American farms
  2. CBD is extracted from the hemp stalks through a process that involves heat and pressure.
  3. Delta-8 THC is converted from the CBD
  4. Acetic anhydride is added to the Delta-8 THC to create THC-O


It is worth noting that synthesizing commercial quantities of THC-O is neither a natural nor organic process. THC-O distillate is a highly volatile and flammable substance that should only be produced in an ISO-certified laboratory.

And since THC-O possesses little-to-no scientific research on its effects, the risk of overdoing it is a very possible outcome. Exercising conservative dosing is a requirement for a compound with three to four times the potency of traditional Delta-9 THC. For a more in-depth guide on how to dose THC-O, check out our blog we wrote last week!

Some of the more adverse effects THC-O includes:

  • Hallucinations – In higher doses
  • Increased anxiety – Similar in feeling to consuming too much Delta-9 THC
  • Dizziness
  • Paranoia
  • Sedation
  • Vomiting


While developing THC-O may be a seemingly dangerous ordeal, and the effects deliver an intense psychoactive and borderline psychedelic experience, taking THC-O isn’t all that different from enjoying Delta-8 THC. Despite it being significantly more potent, THC-O is still an incredibly enjoyable cannabinoid.

If you have been on the fence about trying the THC-O Disposables Series, worry not! Between this article and our Dosing Guide we published last week, exercising responsible use of THC-O products doesn’t have to be a scary ordeal. And whether you choose to try our THC-O products or a different company, be sure to verify the products are backed by a Certificate of Analysis conducted by a third-party laboratory.

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